Thermo Fisher Scientific ATP13A2 Polyclonal Antibody, Biotin
ATP13A2 단백질을 표적하는 Biotin 결합 폴리클로날 항체로, 인간 및 생쥐 시료에 반응합니다. Western blot과 IHC에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 신경퇴행성 질환 연구에 적합한 연구용 시약입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 2 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 10–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide within the internal region of residues 200–300 of the human ATP13A2 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.75 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152124 |
Product Specific Information
- Suggested positive control: Human and mouse brain membrane prep lysate.
Target Information
Neurodegenerative disorders such as Parkinson’s and Alzheimer’s disease cause motor and cognitive dysfunction and belong to a heterogeneous group of common and disabling disorders.
ATP13A2, also known as PARK9, is a neuronal P-type ATPase gene underlying an autosomal recessive form of early-onset parkinsonism with pyramidal degeneration and dementia.
ATP13A2 protein is located in the membrane of lysosomes and is most strongly expressed in the brain, especially in the substantia nigra, a region known to play a central role in Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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