Thermo Fisher Scientific ATP13A2 Polyclonal Antibody, DyLight 650
DyLight 650 형광 표지된 ATP13A2 폴리클로날 항체로 인간 및 생쥐 시료에 반응. Western blot과 IHC에 적합하며, 신경퇴행성 질환 연구용으로 권장. 항원 친화 크로마토그래피로 정제된 고순도 제품.
- 판매단위
- pk
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Thermo Fisher Scientific ATP13A2 Polyclonal Antibody, DyLight 650
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (IHC) | 10–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide within the internal region of residues 200–300 of the human ATP13A2 protein |
| Conjugate | DyLight™ 650 |
| Excitation / Emission Max | 651 / 673 nm |
| Form | Liquid |
| Concentration | 0.75 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 50 mM sodium borate |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155407 |
Product Specific Information
Suggested positive control: human and mouse brain membrane prep lysate.
Target Information
Neurodegenerative disorders such as Parkinson and Alzheimer disease cause motor and cognitive dysfunction and belong to a heterogeneous group of common and disabling disorders.
ATP13A2, otherwise known as PARK9, is a neuronal P-type ATPase gene underlying an autosomal recessive form of early-onset parkinsonism with pyramidal degeneration and dementia.
ATP13A2 protein is located in the membrane of lysosomes and is expressed most strongly in the brain, especially in the substantia nigra, a region known to play a central role in Parkinson’s disease.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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