Thermo Fisher Scientific OX40/CD134/ TNFRSF4 (Immuno-Oncology Target) Monoclonal Antibody (OX40/3108)
OX40/CD134 단클론 항체로 인간 및 침팬지 반응성. 면역조직화학, 유세포분석, ELISA 등 다양한 응용 가능. 단백질 A/G 정제, 1 mg/mL 농도, PBS 저장. 암 면역치료 연구용으로 적합.
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Thermo Fisher Scientific OX40/CD134/TNFRSF4 Monoclonal Antibody (OX40/3108)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | Assay-dependent |
| Peptide Array | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Chimpanzee, Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX40/3108 |
| Immunogen | Recombinant fragment of human OX40 (CD134) protein (around aa 59–205) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
OX40 (CD134) is a protein receptor expressed on the surface of T cells, which plays a key role in immune regulation. Activation of OX40 enhances T cell proliferation and survival, strengthening immune responses against cancer and infections. OX40 agonists are under investigation as potential immunotherapy agents, showing promise in preclinical and clinical studies. They may also improve the efficacy of chemotherapy and checkpoint inhibitors, and have potential applications in autoimmune and allergic diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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