Thermo Fisher Scientific OX40/CD134/TNFRSF4 (Immuno-Oncology Target) Monoclonal Antibody (OX40, 3427)
OX40/CD134 단일클론 항체로 인간 및 침팬지 반응성 보유. 면역조직화학(IHC) 및 펩타이드 어레이에 사용 가능. 액상 형태, Protein A/G 정제, 4°C 보관. 암 면역치료 연구에 적합한 면역항암 타깃 항체.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chimpanzee, Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX40, 3427 |
| Immunogen | Recombinant fragment of human OX40 (CD134) protein (around aa 59–205) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature (RT).
- For formalin-fixed tissues: Heat tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, then cool at RT for 20 min.
Target Information
OX40 (CD134) is a protein receptor expressed on T cells, crucial for immune system activation. Upon stimulation, OX40 enhances T cell proliferation and survival, strengthening immune responses against cancer and infections.
OX40 agonists have demonstrated potential in immuno-oncology as they can improve efficacy of chemotherapy and checkpoint inhibitors, and may also be applicable in autoimmune and allergic disease research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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