Thermo Fisher Scientific Patched1 Monoclonal Antibody (OTI6C10), TrueMAB
Human PTCH1 단백질(aa 770-1027)을 인식하는 Mouse IgG1 단클론 항체. Western blot에 최적화되어 있으며, 1:2,000 희석 비율로 사용 가능. 액상 형태로 제공되며, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용.
- 판매단위
- pk
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Thermo Fisher Scientific Patched1 Monoclonal Antibody (OTI6C10), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6C10 |
| Immunogen | Human recombinant protein fragment (aa 770–1027 of human PTCH1) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly.
Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full-length sequences and biological validity cannot be determined currently.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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