Thermo Fisher Scientific NAB2 Monoclonal Antibody (OTI3H5), TrueMAB
NAB2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(P) 분석에 최적화됨. 인간 유래 NAB2 단백질(aa 178–442)을 면역원으로 제작. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Thermo Fisher Scientific NAB2 Monoclonal Antibody (OTI3H5), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 178–442 of human NAB2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Transcriptional control is regulated by interactions between DNA-bound transcription factors such as Egr-1/NGFI-A and coregulatory proteins NAB1 and NAB2. These corepressors contain conserved domains (NCB1 and NCD2) responsible for binding and repression functions. NAB2 localizes to the nucleus and may regulate NGFI-A activity, cell division, differentiation, and apoptosis. It has a predicted molecular mass of 56 kDa and is located on chromosome 12q13.3–14.1, a region associated with various solid tumors, lipomas, and liposarcomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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