Thermo Fisher Scientific FADD Polyclonal Antibody
FADD 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보존되어 있으며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within mouse FADD (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% Glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802692 |
Target Information
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates apoptotic signaling. Through its C-terminal death domain, it can be recruited by Fas receptor (TNFRSF6), TNFRSF25, and TRAIL receptor (TNFSF10), participating in death signaling initiated by these receptors. Interaction with these receptors exposes the N-terminal effector domain, allowing recruitment of caspase-8 and activation of the cysteine protease cascade. Knockout studies in mice indicate its importance in early T cell development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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