Thermo Fisher Scientific Fumarase Monoclonal Antibody (GT548)
Fumarase 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체(GT548). Western blot 및 Immunocytochemistry에 적합하며, 인간, 생쥐, 랫드에 반응. Protein G로 정제된 액상 항체로 장기 보관 시 -20°C에서 안정적 유지 가능.
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Thermo Fisher Scientific Fumarase Monoclonal Antibody (GT548)
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
- Immunocytochemistry (ICC/IF): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT548 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Fumarate hydratase (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735187 |
Product Specific Information
- Positive Control: 293T, mouse liver, rat liver
- Predicted Reactivity: Zebrafish (90%), Pig (98%), Chicken (91%), Sheep (99%), Chimpanzee (99%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle (Krebs cycle) and catalyzes the formation of L-malate from fumarate. It exists in both cytosolic and N-terminal extended mitochondrial forms. The mitochondrial form is generated by removal of the extension. This enzyme functions as a homotetramer and is similar to thermostable class II fumarases. Mutations in this gene can cause fumarase deficiency, leading to progressive encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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