Thermo Fisher Scientific TNFAIP8 Polyclonal Antibody
TNFAIP8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 최적화됨. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TNFAIP8 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 71–116 of Human TNFAIP8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719301 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
TNFalpha-IP 8 (tumor necrosis factor, alpha-induced protein 8), also known as NFkappa B-inducible DED-containing protein (NDED), SCC-S2, or TNF-induced protein GG2-1, is a 198 amino acid cytoplasmic protein induced by NFkappa B and TNF.
Its induction by TNF depends on NFkappa B activation. TNFalpha-IP 8 negatively mediates apoptosis and may play a role in tumor progression. It specifically inhibits caspase-8 activity, leading to inhibition of BID cleavage and caspase-3 activation during TNF-mediated apoptosis.
TNFalpha-IP 8 is expressed at high levels in thymus, bone marrow, lymph node, spleen, thyroid, placenta, and various tumor tissues, as well as fetal lung, liver, and kidney. It exists as three isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.