Thermo Fisher Scientific FCGR3A Monoclonal Antibody (2B11)
Thermo Fisher Scientific의 FCGR3A 단클론 항체(2B11)는 인간 CD16 단백질을 인식하며 Western blot 및 ELISA에 적합합니다. 비결합형 액상 형태로 제공되며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B11 |
| Immunogen | FCGR3A (AAH17865.1, 17 a.a. approximately 254 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
GMRTEDLPKA VVFLEPQWYR VLEKDSVTLK CQGAYSPEDN STQWFHNESL ISSQASSYFI
DAATVDDSGE YRCQTNLSTL SDPVQLEVHI GWLLLQAPRW VFKEEDPIHL RCHSWKNTAL
HKVTYLQNGK GRKYFHHNSD FYIPKATLKD SGSYFCRGLV GSKNVSSETV NITITQGLAV
STISSFFPPG YQVSFCLVMV LLFAVDTGLY FSVKTNIRSS TRDWKDHKFK WRKDPQDKTarget Information
CD16 (FCGR3A) encodes a receptor that recognizes the Fc portion of immunoglobulin G and is involved in immune complex clearance, antibody-dependent cellular cytotoxicity, and enhancement of viral infection.
This gene shares high similarity with FCGR3B, located nearby on chromosome 1.
- Expression: On NK cells as an integral membrane glycoprotein
- Related Diseases: Immunodeficiency 20, Herpes Zoster, Systemic Lupus Erythematosus, Alloimmune Neonatal Neutropenia
- Alternative Splicing: Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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