Thermo Fisher Scientific Dnmt3b Polyclonal Antibody
Dnmt3b 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western Blot과 Flow Cytometry에 사용 가능하며, KLH 결합 합성 펩타이드(aa 251-350)를 면역원으로 제작되었습니다. 단백질 A로 정제된 액상 형태로, -20°C에서 보관합니다.
- 카탈로그번호
- BS-20680R
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:300
Flow Cytometry (Flow)
- Tested Dilution: 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Dnmt3b (amino acids 251–350) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CpG methylation is an epigenetic modification important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have shown that DNA methylation is essential for mammalian development. This gene encodes a DNA methyltransferase involved in de novo methylation, primarily localized to the nucleus and developmentally regulated. Mutations in this gene cause immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described; the full-length sequences of variants 4 and 5 have not been determined.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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