Thermo Fisher Scientific GPD2 Polyclonal Antibody
Thermo Fisher Scientific의 GPD2 폴리클로날 항체는 인간, 생쥐, 랫드에 반응하며 Western blot 및 ELISA에 적합합니다. 미토콘드리아 글리세로인산 탈수소효소(GPD2)를 표적하며, 고순도 친화 크로마토그래피로 정제된 액상 항체입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA593093
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: View 1 publication
ELISA
- Tested Dilution: 1 µg/mL
- Publications: View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Hamster |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 25–325 of human GPD2 (NP_0003993) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.86 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806620 |
Product Specific Information
Immunogen Sequence:
SQFAHYRRKQ MNLAYVKAAD CISEPVNREP PSREAQLLTL QNTSEFDILV IGGGATGSGC ALDAVTRGLK TALVERDDFS SGTSSRSTKL IHGGVRYLQK AIMKLDIEQY RMVKEALHER ANLLEIAPHL SAPLPIMLPV YKWWQLPYYW VGIKLYDLVA GSNCLKSSYV LSKSRALEHF PMLQKDKLVG AIVYYDGQHN DARMNLAIAL TAARYGAATA NYMEVVSLLK KTDPQTGKVR VSGARCKDVL TGQEFDVRAK CVINATGPFT DSVRKMDDKD AAAICQPSAG VHIVMPGYYS P
Positive Samples:
MCF7, THP-1, SW480, Mouse skeletal muscle, Mouse liver, Mouse pancreas, Mouse brain
Cellular Location:
Mitochondrion
Target Information
Mitochondrial glycerophosphate dehydrogenase (EC 1.1.99.5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which transfers reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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