Thermo Fisher Scientific CRG-L2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide: L(160) V G K A D E K A S E H H S P Q A(176) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CRG-L2,uniProtId:Q6ZMI3-1,ncbiNodeId:9606,antigenRange:160-176,antigenLength:551,antigenImageFileName:PA1-4325_CRG-L2_Q6ZMI3-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4325_CRG-L2_Q6ZMI3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2111614

Product Specific Information

PA1-4325 detects CRG-L2 in human samples.

PA1-4325 has been successfully used in Western blotting procedures. The predicted molecular weight is 48 kDa. By Western blot, this antibody detects a protein often above ~50 kDa representing CRG-L2. This protein can form dimers.

PA1-4325 immunizing peptide corresponds to amino acid residues 160-176 of human CRG-L2.

Target Information

CRG-L2 is a protein that contains olfactomedin-like and collagen-like domains. The encoded protein, which exists in both transmembrane and secreted forms, promotes formation of the nodes of Ranvier in the peripheral nervous system. Mutations in this gene cause a form of lethal congenital contracture syndrome in human patients. Autoantibodies to the encoded protein have been identified in sera form patients with multifocal motor neuropathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.