Thermo Fisher Scientific TCF4/TCF12 Polyclonal Antibody
TCF4/TCF12 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, 인간·생쥐·랫드 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 -20°C 보관.
- 카탈로그번호
- PA5106756
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific TCF4/TCF12 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TCF4 (Accession P15884), corresponding to amino acid residues K596–P646 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854424 |
Product Specific Information
This antibody detects endogenous levels of total TCF4/12.
Target Information
T cell factors (TCFs) are a family of DNA-binding transcriptional activators essential for lymphoid cell development. These transcription factors are activated by the Wnt-1 and Wingless pathways and contain a conserved high mobility group (HMG) 1 box that mediates DNA binding.
TCF-4 mainly localizes in the cytoplasm and is transported into the nucleus bound to beta-catenin. The TCF-4/beta-catenin complex induces expression of Wnt target genes, including multiple cancer-associated genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-106756_TCF4TCF12_P15884-1_Rabbit.svg, PA5-106756_TCF4TCF12_P15884-1_Rabbit_PDP.jpeg)
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