Thermo Fisher Scientific GTF3A Polyclonal Antibody
Human GTF3A 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합. 고순도 Affinity Chromatography로 정제된 액상 형태이며, PBS/glycerol 버퍼에 보관. 연구용으로 RNA polymerase III 관련 전사 인자 분석에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GTF3A (Accession Q92664), corresponding to amino acid residues V6–K56 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854426 |
Product Specific Information
Antibody detects endogenous levels of total GTF3A.
Target Information
The GTF3A gene encodes a zinc finger protein with nine Cys[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor that induces transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes, called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits TFIIIC, TFIIIB, and RNA polymerase III to form the complete transcription complex. In mammals, translation is thought to initiate from a non-AUG site based on sequence analysis and protein homology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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