Thermo Fisher Scientific eIF2b gamma Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human EIF2B3(Accession Q9NR50), corresponding to amino acid residues F266-L316. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:eIF2b gamma,uniProtId:Q9NR50-1,ncbiNodeId:9606,antigenRange:266-316,antigenLength:452,antigenImageFileName:PA5-106759_eIF2b_gamma_Q9NR50-1_Rabbit.svg,antigenImageFileNamePDP:PA5-106759_eIF2b_gamma_Q9NR50-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2854427

Product Specific Information

Antibody detects endogenous levels of total EIF2B3.

Target Information

EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutations in each of the five subunits of translation initiation factor eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter. EIF2B3 has also been identified as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.