Thermo Fisher Scientific FZD10 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human Frizzled-10 (FZD10). Validated for WB and IHC applications. Provides high specificity and sensitivity for research use. Supplied as liquid form at 1 mg/mL concentration.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 121–581 of Human Frizzled 10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544650 |
Product Specific Information
- Recommended positive controls: H1299, NIH-3T3, JC, BCL-1
- Predicted reactivity: Mouse (100%), Rat (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
FZD10 (Frizzled-10) is a 581 amino acid protein belonging to the G-protein coupled receptor Fz/Smo family. It contains a signal peptide, a cysteine-rich domain in the N-terminal, seven transmembrane domains, and a C-terminal PDZ domain-binding motif.
FZD10 is involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and acts as a receptor for Wnt proteins.
It is highly expressed in placenta, fetal kidney, fetal lung, brain cerebellum, cerebral cortex, medulla, and spinal cord, with very low levels in total brain, frontal lobe, temporal lobe, putamen, adult brain, heart, lung, and skeletal muscle.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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