Thermo Fisher Scientific Filamin B Polyclonal Antibody
Filamin B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능. Human 및 Mouse 반응성. 고순도 Protein A 정제, 안정적인 PBS/BSA/glycerol buffer 구성. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 30–269 of Filamin B (Uniprot ID: O75369) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.296 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11156801 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2, U87-MG, NIH-3T3
- Predicted reactivity: Mouse (98%), Rat (98%), Chicken (97%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target, the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung, and thymus. It is predominantly expressed in many malignant tissues, such as tumors of the brain, colon, and lymph node.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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