Thermo Fisher Scientific PDE3B Polyclonal Antibody
PDE3B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간 PDE3B에 특이적이며, 고순도의 Affinity chromatography로 정제됨. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PDE3B (Accession Q13370), corresponding to amino acid residues P320–P370 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853067 |
Product Specific Information
Antibody detects endogenous levels of total PDE3B.
Target Information
Cyclic nucleotide phosphodiesterase with dual specificity for the second messengers cAMP and cGMP, key regulators of many physiological processes. May play a role in fat metabolism and regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6, assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and involved in angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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