Thermo Fisher Scientific CLCNKB Polyclonal Antibody
인간 CLCNKB 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도, PBS/glycerol 저장. 연구용으로만 사용.
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Thermo Fisher Scientific CLCNKB Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CLCNKB (Accession P51801), corresponding to amino acid residues G6–L56 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853069 |
Product Specific Information
Antibody detects endogenous levels of total CLCNKB.
Target Information
Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least nine mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini.
Mutations in CLCNKB result in autosomal recessive Type III Bartter Syndrome.
CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence), and both expressed in mammalian kidney.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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