Thermo Fisher Scientific Ly-108 Monoclonal Antibody (eBio13G3-19D (13G3-19D)), eBioscience

Applications and Tested Dilutions

Product Specifications

Available Conjugated Formats

• APC ([17-1508-82])
• Biotin ([13-1508-82])
• Functional Grade ([16-1508-82])
• NovaFluor Blue 660-120S ([M050T03B08-A])
• NovaFluor Red 685 ([M050T03R02-A])
• NovaFluor Red 700 ([M050T03R03-A])
• NovaFluor Red 755 ([M050T03R06-A])
• NovaFluor Yellow 610 ([M050T03Y03-A])
• NovaFluor Yellow 660 ([M050T03Y04-A])
• NovaFluor Yellow 700 ([M050T03Y06-A])
• NovaFluor Yellow 755 ([M050T03Y08-A])
• PE ([12-1508-80])
• Custom conjugation available upon request

Product Specific Information

The eBio13G3-19D monoclonal antibody reacts with mouse Ly108, a homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6).
Ly108, also known as NTB-A, is expressed on NK, T, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and IFN-γ expression and is associated with immune regulation in X-linked lymphoproliferative disease.

• Strain Reactivity: No difference observed between C57BL/6 and BALB/c mice; other strains not tested.
• Applications Reported: Flow cytometry, immunoprecipitation, and Western blot.
• Applications Tested: Flow cytometric analysis of mouse splenocytes and thymocytes at ≤0.5 µg/test (in 100 µL). Cell count range: 10⁵–10⁸ cells/test.
  Antibody titration recommended for optimal performance.

Purity: >90% (SDS-PAGE)
Aggregation: <10% (HPLC)
Filtration: 0.2 µm post-manufacturing filtered

Target Information

Ly108 (SLAMF6) is expressed on NK, B, and T cells in mice. Activation of Ly108 enhances NK cell activity and IFN-γ expression, playing a role in immune signaling.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.