Thermo Fisher Scientific SCG5 Polyclonal Antibody
SCG5 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB 및 IHC(P) 분석에 적합. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제. -20°C 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SCG5 (Accession P05408), corresponding to amino acid residues Q111–G161 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2853297 |
Product Specific Information
Antibody detects endogenous levels of total SCG5.
Target Information
Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway.
Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport to later compartments of the secretory pathway where it is proteolytically matured and activated.
Also required for cleavage of PCSK2 but does not appear to be involved in its folding.
Plays a role in regulating pituitary hormone secretion.
The C-terminal peptide inhibits PCSK2 in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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