Thermo Fisher Scientific NCALD Polyclonal Antibody
NCALD 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot과 IHC(P)에서 검증됨. Human, Mouse, Rat 등 다양한 종에 반응. Affinity chromatography로 정제된 액상 형태로, -20°C에서 보관. 연구용으로만 사용 가능.
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- PA5103964
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NCALD (Accession P61601), corresponding to amino acid residues D21–T71 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853296 |
Product Specific Information
Antibody detects endogenous levels of total NCALD.
Target Information
This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium-binding loops. It is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-Golgi network. The protein is thought to regulate G protein-coupled receptor signal transduction. Several alternatively spliced variants have been identified, all encoding the same protein; additional variants may exist but their biological validity remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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