Thermo Fisher Scientific NAV3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human NAV3(Accession Q8IVL0), corresponding to amino acid residues M1497-S1547. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NAV3,uniProtId:Q8IVL0-1,ncbiNodeId:9606,antigenRange:1497-1547,antigenLength:2385,antigenImageFileName:PA5-103969_NAV3_Q8IVL0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103969_NAV3_Q8IVL0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2853301

Product Specific Information

Antibody detects endogenous levels of total NAV3.

Target Information

Neuron navigator 3 (NAV3), also known as pore membrane and/or filamentinteracting-like protein 1 (POMFIL1), unc-53 homolog 3 (unc53H3) or STEERIN3, is a 2,385 amino acid protein that localizes to the nuclear outer membrane and plays a role in neuron regeneration. Existing as three alternatively spliced isoforms, Neuron navigator 3 is highly expressed in adult and fetal brain and is found at moderate to low levels in ovary, lung, testis, placenta and heart. Neuron navigator 3 is thought be involved in the regulation of IL-2 production and contains one CH (calponin-homology) domain, three N-terminal hydrophobic domains, multiple N-glycosylation sites, three ATP/GTP-binding A motifs (P loops) and several phosphorylation sites.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.