
Thermo Fisher Scientific NAV3 Polyclonal Antibody
NAV3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며 인간 시료에서 반응. Affinity chromatography로 정제된 액상 형태로, PBS/glycerol buffer에 보관. 신경 재생 관련 단백질 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NAV3 (Accession Q8IVL0), corresponding to amino acid residues M1497–S1547. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853301 |
Product Specific Information
Antibody detects endogenous levels of total NAV3.
Target Information
Neuron navigator 3 (NAV3), also known as pore membrane and/or filament-interacting-like protein 1 (POMFIL1), unc-53 homolog 3 (unc53H3), or STEERIN3, is a 2,385 amino acid protein localized to the nuclear outer membrane and involved in neuron regeneration.
NAV3 exists as three alternatively spliced isoforms, highly expressed in adult and fetal brain, and moderately to lowly expressed in ovary, lung, testis, placenta, and heart.
It is thought to regulate IL-2 production and contains one CH (calponin-homology) domain, three N-terminal hydrophobic domains, multiple N-glycosylation sites, three ATP/GTP-binding A motifs (P loops), and several phosphorylation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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