Thermo Fisher Scientific S100A10 Monoclonal Antibody (6F4-E6-D5-C10)
S100A10 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. Western blot, IHC, ICC/IF, IP에 적합하며 인간, 마우스, 랫트에 반응. 고순도 친화 크로마토그래피 정제, 1.5 mg/mL 농도, 장기 보관 시 -20°C 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:200 | View 1 publication |
| Immunoprecipitation (IP) | 1:100 | View publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6F4-E6-D5-C10 |
| Immunogen | Purified recombinant human S100A10 protein fragments expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2717244 |
Target Information
The S-100 family of calcium-activated proteins interact with various target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II. This association is not required for plasma membrane localization or plasminogen activation.
Additionally, S-100A10 acts as a cellular chaperone for hepatitis B virus (Hep B) polymerase, facilitating partial nuclear localization and suggesting a role for S-100A10 and intracellular calcium in viral replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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