Thermo Fisher Scientific Pan Ras Polyclonal Antibody
Pan Ras 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF, Flow Cytometry에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| Flow Cytometry (Flow) | 1:100–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within Human Ras amino acids 11–60 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% Glycerol, 0.2% BSA |
| Contains | 0.05% Sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at –20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802748 |
Target Information
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The encoded proteins function in signal transduction pathways and can bind GTP and GDP, possessing intrinsic GTPase activity. These proteins undergo cycles of de- and re-palmitoylation, regulating exchange between the plasma membrane and Golgi apparatus. Mutations in this gene cause Costello syndrome and are implicated in various cancers such as bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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