Thermo Fisher Scientific CDK7 Polyclonal Antibody, MaxPab
CDK7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western Blot 및 in situ PLA에 사용 가능. 인간 CDK7 full-length 단백질을 면역원으로 제작. 고순도 Affinity chromatography 정제. 연구용으로만 사용.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
in situ PLA (PLA)
- Tested Dilution: 1:1,200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CDK7 (NP_001790.1, 1 a.a. ~ 346 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MALDVKSRAK RYEKLDFLGE GQFATVYKAR DKNTNQIVAI KKIKLGHRSE AKDGINRTAL REIKLLQELS HPNIIGLLDA FGHKSNISLV FDFMETDLEV IIKDNSLVLT PSHIKAYMLM TLQGLEYLHQ HWILHRDLKP NNLLLDENGV LKLADFGLAK SFGSPNRAYT HQVVTRWYRA PELLFGARMY GVGVDMWAVG CILAELLLRV PFLPGDSDLD QLTRIFETLG TPTEEQWPDM CSLPDYVTFK SFPGIPLHHI FSAAGDDLLD LIQGLFLFNP CARITATQAL KMKYFSNRPG PTPGCQLPRP NCPVETLKEQ SNPALAIKRK RTEALEQGGL PKKLIF
Target Information
The trimeric complex of CDK7, cyclin H, and MNAT1 functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, involved in transcription initiation and DNA repair. This complex links transcription regulation and the cell cycle. The bound complex is important in normal double-strand break repair associated with BRCA1. CDK7 may be a target of germline cancer-inducing mutations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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