Thermo Fisher Scientific CDK5 Monoclonal Antibody (1A2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM, kappa

Class

Monoclonal

Type

Antibody

Clone

1A2

Immunogen

CDK5 (AAH05115, 195 a.a. approximately 292 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDK5,uniProtId:Q00535-1,ncbiNodeId:9606,antigenRange:195-292,antigenLength:292,antigenImageFileName:H00001020-M01A_CDK5_Q00535-1_House_mouse.svg,antigenImageFileNamePDP:H00001020-M01A_CDK5_Q00535-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: LANAGRPLFP GNDVDDQLKR IFRLLGTPTE EQWPSMTKLP DYKPYPMYPA TTSLVNVVPK LNATGRDLLQ NLLKCNPVQR ISAEEALQHP YFSDFCPP

Target Information

CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.