Thermo Fisher Scientific BCL11A Polyclonal Antibody
BCL11A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 최적화됨. Human 시료에 반응하며 Protein A 및 Antigen affinity chromatography로 정제됨. PBS buffer에 0.09% sodium azide 포함. 연구용으로만 사용 가능.
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Applications
Tested Application
- Western Blot (WB): 1:1,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between amino acids 806–835 from the C-terminal region of human BCL11A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2544135 |
Target Information
This gene encodes a C2H2 type zinc-finger protein similar to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia and may function as a leukemia disease gene through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated and may be involved in lymphoma pathogenesis, as translocations associated with B-cell malignancies deregulate its expression. Multiple transcript variants encoding several different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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