
Thermo Fisher Scientific PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), APC
인간 PARP1 (cleaved Asp214)을 인식하는 재조합 토끼 단클론 항체로, APC 형광체로 결합됨. Flow Cytometry에 최적화되어 있으며, 651/660 nm의 형광 특성을 가짐. 단백질 A/G로 정제되었고, 4°C에서 보관.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PARP-H8 |
| Immunogen | A synthetic peptide corresponding to residues surrounding Asp214 of human PARP |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897295 |
Additional Formats
- Unconjugated (MA5-37112)
- FITC (MA5-37114)
- PE (MA5-37113)
- Custom conjugation available on request
Target Information
Poly ADP-Ribose Polymerase (PARP) uses NAD⁺ as a substrate to catalyze the transfer of ADP-ribose to various nuclear protein acceptors. Proteolysis of PARP to its stable 85 kDa fragment is an early marker of apoptosis and is mediated by the caspase CPP32 protein. Cleavage occurs between Asp216 and Gly217, a site conserved across species.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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