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Thermo Fisher Scientific PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), FITC
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FITC로 표지된 재조합 토끼 단클론 항체로, 인간 PARP1 (cleaved Asp214)을 특이적으로 인식합니다. Flow Cytometry에 최적화되어 있으며, Protein A/G로 정제된 액상 형태입니다. 4°C 어둠에서 보관하며, 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific MA537360 PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), FITC 10 tests pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), FITC
Applications
Flow Cytometry (Flow)
- Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PARP-H8 |
| Immunogen | A synthetic peptide corresponding to residues surrounding Asp214 of human PARP |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897294 |
Additional Formats
- Unconjugated (MA5-37112)
- APC (MA5-37115)
- PE (MA5-37113)
- Custom conjugation available upon request
Target Information
Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form, NAD) as a substrate to catalyze the transfer of ADP-ribose to a variety of nuclear protein acceptors.
Proteolysis of PARP to its stable 85 kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein.
Cleavage occurs between Asp216 and Gly217, a site conserved across species.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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