Thermo Fisher Scientific LRP12 Monoclonal Antibody (7B8A3)
Human LRP12 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 ELISA에 적합합니다. 단백질 G로 정제된 액상 형태이며, 1 mg/mL 농도로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7B8A3 |
| Immunogen | Purified recombinant fragment of human LRP12 (AA: extra 355–492) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090887 |
Target Information
Members of the LDL receptor gene family, including LDLR (low density lipoprotein receptor), LRP1 (low density lipoprotein related protein), Megalin (GP330), VLDLR (very low density lipoprotein receptor), and ApoER2, are characterized by cysteine-rich class A repeats, EGF-like repeats, YWTD repeats, and an O-linked sugar domain.
LRP12 (also designated ST7) is a member of this family involved in internalization of lipophilic molecules and/or signal transduction. It interacts with RACK1, MADHIP, and Integrin beta-1-binding protein 3, and is widely expressed in heart, skeletal muscle, brain, lung, placenta, and pancreas. Overexpression of LRP12 may be associated with oral tumors, suggesting a potential oncogenic role.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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