Thermo Fisher Scientific PABP4 Polyclonal Antibody
PABP4 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 응용에 적합. 인간 PABPC4(594-644) 영역을 면역원으로 사용. 액상 형태, 0.20 mg/mL 농도, 4°C 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PABP4 Polyclonal Antibody
Thermo Fisher Scientific PABP4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 594 and 644 of human Poly(A)-binding protein 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3′ ends of most eukaryotic mRNAs.
PABPC4 (also known as IPABP) is an activation-induced T-cell mRNA encoding a protein whose expression increases approximately 5-fold upon T-cell activation.
It contains four RNA-binding domains and a proline-rich C terminus, and is primarily localized to the cytoplasm.
PABPC4 may regulate the stability of labile mRNA species in activated T cells and is also known as APP1, expressed on thrombin-activated rabbit platelets.
It may be involved in protein translation regulation in platelets and megakaryocytes or in the binding/stabilization of polyadenylates in platelet dense granules.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.