Thermo Fisher Scientific EXO5 Polyclonal Antibody
EXO5 단백질을 표적으로 하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 Flow cytometry에 사용 가능. Rabbit IgG 호스트로 제작되었으며, 높은 특이성과 안정성을 제공. 단백질 A 및 항원 친화 크로마토그래피로 정제된 액상 형태.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Hamster, Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 166–193 amino acids from the central region of human DEM1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.0 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541480 |
Target Information
Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair.
Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage.
Has both 5′–3′ and 3′–5′ exonuclease activities with a strong preference for 5′-ends.
Acts as a sliding exonuclease that loads at ssDNA ends and then slides along the ssDNA prior to cutting; however, the sliding and the 3′–5′ exonuclease activities are abolished upon binding to the replication protein A (RPA) complex that enforces 5′ directionality activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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