Thermo Fisher Scientific Arylsulfatase G Polyclonal Antibody
Thermo Fisher Scientific의 Arylsulfatase G Polyclonal Antibody는 마우스 ARSG 단백질을 인식하는 sheep 유래 IgG 항체입니다. Western blot과 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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- PA547640
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CHO-derived recombinant mouse Arylsulfatase G (ARSG) Gly17–Val525 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607594 |
Product Specific Information
In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant mouse ARSA, recombinant human ARSB, and ARSJ is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Sulfatases such as ARSG hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They play roles in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules.
This gene encodes a novel arylsulfatase with activity toward pseudosubstrates such as p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate.
The unprocessed protein is active as a 63-kDa monomer and exhibits an acidic pH optimum typical of lysosomal sulfatases. The protein accumulates within lysosomes and is a glycoprotein that binds specifically to mannose 6-phosphate receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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