Thermo Fisher Scientific N-Ras Polyclonal Antibody
Thermo Fisher Scientific의 N-Ras Polyclonal Antibody는 인간 NRAS 단백질을 인식하는 토끼 다클론 항체입니다. Western blot, IHC, ICC/IF에 사용 가능하며 0.5 mg/mL 농도의 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C에서 보관이 권장됩니다.
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- PA514833
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | - | View 3 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between amino acids 147–179 of the C-terminal region of human NRAS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2154238 |
Product Specific Information
This antibody is predicted to react with porcine based on sequence homology.
Target Information
NRAS (GTPase NRas) is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the NRAS gene are associated with juvenile myelomonocytic leukemia (JMML) and Noonan syndrome 6.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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