Thermo Fisher Scientific DTNA Polyclonal Antibody
DTNA 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 고순도의 Affinity Chromatography 정제 제품입니다. PBS 기반 버퍼에 50% 글리세롤이 포함되어 안정성이 우수합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 240–480 of human DTNA (NP_0013812) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.03 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804833 |
Product Specific Information
Immunogen sequence:
PVECSYCHSE SMMGFRYRCQ QCHNYQLCQD CFWRGHAGGS HSNQHQMKEY TSWKSPAKKL TNALSKSLSC ASSREPLHPM FPDQPEKPLN LAHIVDTWPP RPVTSMNDTL FSHSVPSSGS PFITRSSPPK DSEVEQNKLL ARAAPAFLKG KGIQYSLNVA DRLADEHVLI GLYVNMLRNN PSCMLESSNR LDEEHRLIAR YAARLAAESS SSQPPQQRSA PDISFTIDAN KQQRQLIAEL E
Positive Samples: U-87MG, Mouse brain
Cellular Location: Cell junction, Cell membrane, Cytoplasm, Synapse
Target Information
The DTNA (Dystrobrevin alpha) protein belongs to the dystrobrevin subfamily of the dystrophin family. It is a component of the dystrophin-associated protein complex (DPC), which includes dystrophin, dystroglycans, sarcoglycans, syntrophins, and alpha-/beta-dystrobrevin. The DPC localizes to the sarcolemma, and its disruption is associated with various forms of muscular dystrophy. Mutations in the DTNA gene are linked to left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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