Thermo Fisher Scientific DTNA Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 240-480 of human DTNA (NP_0013812) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DTNA,uniProtId:Q9Y4J8-1,ncbiNodeId:9606,antigenRange:240-480,antigenLength:743,antigenImageFileName:PA5-88329_DTNA_Q9Y4J8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88329_DTNA_Q9Y4J8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.03 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804833

Product Specific Information

Immunogen sequence: PVECSYCHSE SMMGFRYRCQ QCHNYQLCQD CFWRGHAGGS HSNQHQMKEY TSWKSPAKKL TNALSKSLSC ASSREPLHPM FPDQPEKPLN LAHIVDTWPP RPVTSMNDTL FSHSVPSSGS PFITRSSPPK DSEVEQNKLL ARAAPAFLKG KGIQYSLNVA DRLADEHVLI GLYVNMLRNN PSCMLESSNR LDEEHRLIAR YAARLAAESS SSQPPQQRSA PDISFTIDAN KQQRQLIAEL E; Positive Samples: U-87MG, Mouse brain; Cellular Location: Cell junction, Cell membrane, Cytoplasm, synapse

Target Information

The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.