Thermo Fisher Scientific DUSP3 Polyclonal Antibody
Western blot과 ELISA에 최적화된 Rabbit Polyclonal 항체로, Mouse와 Rat 시료에서 DUSP3 단백질 검출에 사용됩니다. Affinity Chromatography로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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- PA588330
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–185 of human DUSP3 (NP_004081.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.66 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804834 |
Product Specific Information
- Immunogen sequence:
MSGSFELSVQ DLNDLLSDGS GCYSLPSQPC NEVTPRIYVG NASVAQDIPK LQKLGITHVL NAAEGRSFMH VNTNANFYKD SGITYLGIKA NDTQEFNLSA YFERAADFID QALAQKNGRV LVHCREGYSR SPTLVIAYLM MRQKMDVKSA LSIVRQNREI GPNDGFLAQL CQLNDRLAKE GKLKP - Positive Samples: Mouse stomach, Rat kidney
- Cellular Location: Nucleus
Target Information
Protein tyrosine phosphatases (PTPs) are enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Together with tyrosine kinases, PTPs regulate the phosphorylation state of many signaling molecules such as the MAP kinase family.
Dual specificity phosphatases (DSPs) are a subclass of PTPs, selective for dephosphorylating phosphothreonine and phosphotyrosine residues. The prototypical DSP is the VH1 gene in vaccinia virus, expressed during late-stage infection. The shallow active site pocket in VHR allows hydrolysis of phosphorylated serine, threonine, or tyrosine residues, whereas the deeper pocket of typical PTPs restricts specificity to phosphotyrosine.
⚠ WARNING:
This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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