Thermo Fisher Scientific POLK Polyclonal Antibody
POLK 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 ELISA에 적합합니다. Human과 Mouse 시료에 반응하며, Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며, -20°C에서 냉동 보관이 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human POLK (NP_057302.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.98 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804829 |
Product Specific Information
- Immunogen sequence:
MDSTKEKCDS YKDDLLLRMG LNDNKAGMEG LDKEKINKII MEATKGSRFY GNELKKEKQV NQRIENMMQQ KAQITSQQLR KAQLQVDRFA MELEQSRNLS - Positive Samples: 22RV1, SKOV3, U-87MG, Mouse liver
- Cellular Location: Nucleus
Target Information
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although various repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, allow replication through such DNA lesions, ensuring continuity of the replication fork. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile, and POLK is specialized for the extension step of lesion bypass.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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