Thermo Fisher Scientific Calmodulin 3 Polyclonal Antibody
Calmodulin 3 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ELISA에 적합합니다. Human, Mouse, Rat 반응성을 가지며, 고순도 Affinity Chromatography 정제 제품입니다. 연구용으로 세포 내 칼슘 신호 조절 관련 연구에 활용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 40–140 of human CALM3 (NP_0051752) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.43 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805824 |
Product Specific Information
- Positive Samples: Rat testis
- Cellular Location: Cytoplasm, cytoskeleton, spindle, spindle pole
- Immunogen sequence:
LGQNPTEAEL QDMINEVDAD GNGTIDFPEF LTMMARKMKD TDSEEEIREA FRVFDKDGNG YISAAELRHV MTNLGEKLTD EEVDEMIREA DIDGDGQVNY E
Target Information
Calcium binding proteins (CaBP) play a crucial role in calcium-mediated cellular signal transduction in the central nervous system. The CaBP family shares similarity with calmodulin (CaM I) and can functionally substitute or augment CaM I.
CaBP7 contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
CaBP7 and CaBP8 possess unique targeting mechanisms among CaBPs, contributing to differential functional Ca²⁺ sensing.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-89886_Calmodulin_3_P0DP25-1_Rabbit.svg, PA5-89886_Calmodulin_3_P0DP25-1_Rabbit_PDP.jpeg)
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