Thermo Fisher Scientific TPH2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-70 of human TPH2 (NP_7754892) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TPH2,uniProtId:Q8IWU9-1,ncbiNodeId:9606,antigenRange:400-469,antigenLength:490,antigenImageFileName:PA5-89881_TPH2_Q8IWU9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89881_TPH2_Q8IWU9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.14 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805821

Product Specific Information

Positive Samples: U-87MG, SH-SY5Y, Mouse brain, Rat brain

Immunogen sequence: FDPKTTCLQE CLITTFQEAY FVSESFEEAK EKMRDFAKSI TRPFSVYFNP YTQSIEILKD TRSIENVVQD

Target Information

Tryptophan hydroxylase (TPH) is a member of the pterin-dependent aromatic acid hydroxylase family. It catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. TPH is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.