Thermo Fisher Scientific Calbindin D28K Monoclonal Antibody (401025)

Thermo Fisher Scientific Calbindin D28K Monoclonal Antibody (401025)

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human S100P.
• Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin) is a highly conserved 28 kDa calcium-binding protein with broad tissue distribution.
It belongs to a family of low molecular weight calcium-binding proteins (CaBPs), including calmodulin, S-100, parvalbumin, and troponin C.
These proteins share homologous primary structures with conserved EF-hand motifs for Ca²⁺ binding.
Calbindin-D-28K is predominantly found in subpopulations of central and peripheral nervous system neurons, as well as epithelial cells involved in Ca²⁺ transport (e.g., distal tubular cells and cortical collecting tubules of the kidney, and enteric neuroendocrine cells).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.