Thermo Fisher Scientific Pannexin 1 Recombinant Rabbit Monoclonal Antibody (28G5)
Pannexin 1 단백질을 인식하는 재조합 토끼 단클론 항체로, IHC, ICC, Flow Cytometry, ELISA 등 다양한 응용에 적합. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제. 안정적 액상 형태로 -20°C 보관.
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| Flow Cytometry (Flow) | 1:50–1:200 | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 28G5 |
| Immunogen | A synthesized peptide derived from Human PANX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.21 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092513 |
Target Information
The pannexin gene family encodes a second class of putative gap junction proteins and is highly conserved in invertebrates and mammals.
Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels.
Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is more distantly related.
PANX1 forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum.
It may function as a Ca²⁺-leak channel regulating ER Ca²⁺ homeostasis and neural stem/progenitor cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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