Thermo Fisher Scientific HO-1 Polyclonal Antibody
HO-1 단백질을 인식하는 염소 폴리클로날 항체로, Western blot에 최적화됨. Human 시료에 반응하며, TBS 버퍼에 보존. 산화 스트레스 관련 연구에 유용. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-NKVQDSAPVETPRGK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933595 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules biliverdin and carbon monoxide. HO consists of two homologous isozymes: an inducible HO-1 and a constitutively expressed HO-2.
HO-1 is induced by various stimuli, including oxidative stress, inflammatory agents, transforming growth factor beta, and heat shock. The increased expression of HO-1 is considered a cellular defense mechanism against oxidative stress, as elevated HO can generate more bilirubin, an antioxidant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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