Thermo Fisher Scientific alpha Synuclein Polyclonal Antibody
알파 시뉴클레인(alpha Synuclein)을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 IHC(P) 실험에 적합하며, 인간 및 생쥐 시료에 반응. 액상 형태로 제공되며, -20°C에서 보관. 파킨슨병 및 알츠하이머 연구용으로 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-ATGFVKKDQLGK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933590 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_009292.1; NP_000336.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking. Alpha- and beta-synuclein selectively inhibit phospholipase D2, suggesting involvement in signaling pathways.
Mutations in the SNCA gene, encoding alpha-synuclein, are linked to Parkinson’s disease. Alpha-synuclein peptides are also major components of amyloid plaques in Alzheimer’s disease. Multiple alternatively spliced transcripts encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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