Thermo Fisher Scientific DOCK10 Polyclonal Antibody
Rabbit polyclonal antibody targeting human DOCK10 protein region 100–150. Validated for Western blot and immunoprecipitation. Supplied as unconjugated liquid form at 1 mg/mL. For research use only; store at 4°C.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 100 and 150 of human dedicator of cytokinesis 10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
Target Information
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking.
Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors.
This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network.
This gene encodes two transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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