Thermo Fisher Scientific Thyroglobulin Monoclonal Antibody (ZY460)
인간 Thyroglobulin을 인식하는 단클론 항체로 IHC(P)에서 2–10 µg/mL로 검증됨. 마우스 IgG1 형식이며, Protein A로 정제된 액상 제품. 단기 4°C, 장기 -20°C 보관 권장. 갑상선 질환 및 암 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ZY460 |
| Immunogen | Recombinant protein of human Thyroglobulin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Thyroid
- Cellular location: Secreted
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones (T4 and T3).
Thyroid disorders are largely autoimmune in origin, and anti-thyroglobulin autoantibodies were the first to be discovered. Anti-hTG is detected in all thyroid autoimmune diseases (e.g., Hashimoto thyroiditis, Graves disease), with the highest levels observed in Hashimoto thyroiditis. It is also characteristic of thyroid cancer and can be used for monitoring cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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