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Thermo Fisher Scientific PD-L1 (CD274) Monoclonal Antibody (ZY349)
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인간 PD-L1(CD274)을 인식하는 단클론 항체로, IHC와 유세포분석에 적합합니다. 단백질 A로 정제된 액상 항체이며, 0.5 mg/mL 농도로 제공됩니다. 종양 면역회피 연구에 활용 가능하며, 장기 보관 시 -20°C에서 보관합니다.
- 카탈로그번호
- 604-730
- 판매단위
- pk
카탈로그
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마지막 업데이트 2025. 08. 04. 오후 11:15
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Thermo Fisher Scientific 604-730 PD-L1 (CD274) Monoclonal Antibody (ZY349) 100 ug pk판매 단위 pk ·
재고 확인 필요
421,400원VAT 포함 463,540원
Thermo Fisher Scientific · Thermo Fisher Scientific PD-L1 (CD274) Monoclonal Antibody (ZY349)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 0.5–5 µg/10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ZY349 |
| Immunogen | Recombinant human PD-L1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human breast carcinoma
- Cellular location: Membrane
Target Information
Programmed death receptor ligand 1 (PD-L1, also known as B7-H1) is a member of the B7 family. PD-L1 binds to its receptor PD-1, which negatively regulates T-cell receptor (TCR) signaling. This interaction decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be upregulated upon IFN-γ stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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