Thermo Fisher Scientific RPL14 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000
• Recommended positive controls: 293T, Raji
• Predicted reactivity: Mouse (93%), Rat (93%), Xenopus laevis (80%), Dog (98%), Pig (93%), Bovine (93%)

Product Specifications

Product Specific Information

• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.
This gene encodes a ribosomal protein that is a component of the 60S subunit and belongs to the L14E family. It contains a basic region-leucine zipper (bZIP)-like domain and is located in the cytoplasm.
The gene includes a polymorphic trinucleotide (GCT) repeat tract resulting in a stretch of alanine residues. Transcript variants utilizing alternative polyA signals and 5′-terminal exons exist but encode the same protein. Multiple processed pseudogenes are dispersed throughout the genome.

References:

• Aoki M., Diabetes 45:157–164 (1996)
• Tanaka M., Biochem. Biophys. Res. Commun. 243:531–537 (1998)
• Yoshihama M., Genome Res. 12:379–390 (2002)

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.