Thermo Fisher Scientific Chitotriosidase Polyclonal Antibody
인간 Chitotriosidase 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 단기 4°C 보관 및 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 216–463 of Chitotriosidase (Uniprot ID: Q13231) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154366 |
Product Specific Information
- Recommended positive controls: A549, HeLa, Jurkat
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression occurs at a late stage of differentiation of monocytes to activated macrophages. Human macrophages synthesize a functional chitotriosidase, a highly conserved enzyme with strongly regulated expression, which may play a role in degradation of chitin-containing pathogens.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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